EVZIO—an auto-injector designed to be easy to use—provides simple, on-the-spot voice and visual guidance to help those with no medical training administer naloxone during an opioid overdose. EVZIO is not a substitute for emergency medical care.

EVZIO Device

EVZIO is Designed to Be…

Be EVZIO-Ready

Easy to Use

Voice and visual guidance that may help make it easy for care partners to administer naloxone during an opioid overdose

Prefilled auto-injector is used to administer naloxone in the outer thigh through clothing if necessary (even blue jeans) whether face up or face down

EVZIO even reminds care partners to call 911

Easy to Carry

Easy to Carry

Small enough to fit in most pockets so it can be on hand in case of an opioid overdose

Easy to Get

Easy to Get

Through the EVZIO2YOU direct-delivery service, all commercially insured patients pay absolutely nothing out of pocket for their EVZIO prescription

Be EVZIO-Ready

THIS OFFER IS NOT INSURANCE. This offer is valid only in the United States. Program is applicable only for commercially insured patients who utilize the direct delivery service. Offer not valid for patients insured in whole or in part by government programs such as Medicaid, Medicare, Tricare or other federal or state health programs (such as state prescription drug programs). If the patient is eligible for benefits under any such program, the patient cannot use this offer. By using this offer, the patient certifies that he or she will comply with any terms of his or her health insurance contract requiring notification to his or her payer of the existence and/or value of this offer. It is illegal to (or offer to) sell, purchase, or trade this offer. This offer is not transferable. Cannot be combined with any rebate/coupon, free trial, or similar offer for the specified prescription(s). Void where prohibited by law. Cash discount cards are not commercial payers and are not eligible to be used for this program. Kaleo, Inc. reserves the right to rescind, revoke, amend, or terminate this offer without written notice at any time. Savings limits apply. Call (877) 438-9463 for questions regarding eligibility.

Talk to your healthcare provider to learn more about EVZIO.

You can also call 1-855-77-EVZIO (1-855-773-8946) for more information about EVZIO.

INDICATION

What is EVZIO?

EVZIO is a prescription medicine used in adults and children for the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.

EVZIO is to be given right away and does not take the place of emergency medical care. Get emergency medical help right away after the first dose of EVZIO, even if the person wakes up.

EVZIO is safe and effective in children for known or suspected opioid overdose.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about EVZIO?

EVZIO is used to temporarily reverse the effects of opioid medicines. The medicine in EVZIO has no effect in people who are not taking opioid medicines. Always carry EVZIO with you in case of an opioid emergency.

Who should not use EVZIO?

Do not use EVZIO if you are allergic to naloxone hydrochloride or any of the ingredients in EVZIO.

What are the ingredients in EVZIO?

Active ingredient: naloxone hydrochloride
Inactive ingredients: sodium chloride, hydrochloric acid to adjust pH, and water

What should I tell my healthcare provider before using EVZIO?

Tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of EVZIO?

EVZIO may cause serious side effects, including:

Common side effects of EVZIO include dizziness and injection site redness.

These are not all of the possible side effects of EVZIO. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click for full Prescribing Information and Patient Information.

INDICATION

What is EVZIO?

EVZIO is a prescription medicine used in adults and children for the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.

EVZIO is to be given right away and does not take the place of emergency medical care. Get emergency medical help right away after the first dose of EVZIO, even if the person wakes up.

EVZIO is safe and effective in children for known or suspected opioid overdose.