EVZIO—an auto-injector designed to be easy to use.
EVZIO is not a substitute for emergency medical care.
The use of EVZIO may result in symptoms of acute opioid withdrawal.
Using EVZIO: Administration steps
Pull EVZIO from the outer case.
Do not go to Step 2 (Do not remove the red safety guard) until you are ready to use EVZIO. If you are not ready to use EVZIO, put it back in the outer case for later use.
Pull off the red safety guard.
To reduce the chance of an accidental injection, do not touch the black base of the auto-injector, which is where the needle comes out. If an accidental injection happens, get medical help right away.
Note: The red safety guard is made to fit tightly. Pull firmly to remove. Do not replace the red safety guard after it is removed.
Place the black end of EVZIO against the outer thigh, through clothing, if needed. Press firmly and hold in place for 5 seconds. If you give EVZIO to an infant less than 1 year old, pinch the middle of the outer thigh before you give EVZIO and continue to pinch while you give EVZIO.
Note: EVZIO makes a distinct sound (click and hiss) when it is pressed against the thigh. This is normal and means that EVZIO is working correctly. Keep EVZIO firmly pressed on the thigh for 5 seconds after you hear the click and hiss sound. The needle will inject and then retract back up into the EVZIO auto-injector and is not visible after use.
After using EVZIO, get emergency medical help right away. If symptoms return after an injection with EVZIO, an additional injection using another EVZIO may be needed. Give additional injections using a new EVZIO auto-injector every 2 to 3 minutes and continue to closely watch the person until emergency help is received. EVZIO does not take the place of emergency medical care.
EVZIO cannot be reused. After use, place the auto-injector back into its outer case. Do not replace the red safety guard.
For more detailed information on how to use EVZIO, click here.