I did not hesitate. Evzio guided me.*

EVZIO—an auto-injector designed to be easy to use—provides simple, on-the-spot voice and visual guidance to help those with no medical training administer naloxone during an opioid overdose. EVZIO is not a substitute for emergency medical care.

ASK YOUR HEALTHCARE PROVIDER IF EVZIO IS RIGHT FOR YOU.
The use of EVZIO may result in symptoms of acute opioid withdrawal.

*Sample story.

A 2-minute conversation with your healthcare provider may help save a life

Anywhere opioids are present there may be a risk of opioid overdose.1-4 In 2017, there were 47,600 deaths due to opioids.3 Additionally, most life-threatening opioid overdoses occur in the home, likely witnessed by friends or family.3,5

Be aware—Be ready

If you or someone you know has been taking prescription opioids for a while, or has recently been prescribed opioids, it’s important that you have a conversation with your healthcare provider to help understand the risks associated with opioids for the treatment of chronic pain.

Although you may be nervous or uncomfortable to have this conversation, it is essential to anyone taking opioids, even if you are taking them as prescribed.2,4,5 Having this 2-minute conversation can help your healthcare provider make sure you are on the right treatment plan for you and your family.

A 2-minute conversation can make all the difference.

3 ways to help you start the conversation with your healthcare provider

Do any of the medications I take increase my risk of opioid overdose?

1

What can I do to help myself, and those around me, manage the risks?

2

What is take-home naloxone and is it something that I need to have?

3

Ask your healthcare provider if you should have EVZIO on hand

EVZIO—an auto-injector designed to be easy to use—provides simple, on-the-spot voice and visual guidance to help those with no medical training administer naloxone during an opioid overdose.

Seek emergency medical care immediately after use. Additional doses of EVZIO may be required until emergency medical assistance becomes available. The use of EVZIO may result in symptoms of acute opioid withdrawal.

References:

  1. EVZIO [prescribing information]. Richmond, VA: kaleo, Inc.
  2. Substance Abuse and Mental Health Services Administration. SAMHSA Opioid Overdose Prevention Toolkit. HHS Publication No. (SMA) 16-4742. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2018.
  3. Centers for Disease Control and Prevention. CDC Wonder: About multiple causes of death, 1999-2017. http://wonder.cdc.gov/mcd-icd10.html. Accessed January 28, 2019.
  4. Federation of State Medical Boards. Guidelines for the chronic use of opioid analgesics. April 2017. https://www.fsmb.org/siteassets/advocacy/policies/opioid_guidelines_as_adopted_april-2017_final.pdf. Accessed January 25, 2019.
  5. Adams JM. Increasing naloxone awareness and use: The role of health care practitioners. JAMA. 2018;319(20):2073-2074.

INDICATION

What is EVZIO?

EVZIO is a prescription medicine used in adults and children for the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.

EVZIO is to be given right away and does not take the place of emergency medical care. Get emergency medical help right away after the first dose of EVZIO, even if the person wakes up.

EVZIO is safe and effective in children for known or suspected opioid overdose.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about EVZIO?

EVZIO is used to temporarily reverse the effects of opioid medicines. The medicine in EVZIO has no effect in people who are not taking opioid medicines. Always carry EVZIO with you in case of an opioid emergency.

Who should not use EVZIO?

Do not use EVZIO if you are allergic to naloxone hydrochloride or any of the ingredients in EVZIO.

What are the ingredients in EVZIO?

Active ingredient: naloxone hydrochloride
Inactive ingredients: sodium chloride, hydrochloric acid to adjust pH, and water

What should I tell my healthcare provider before using EVZIO?

Tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of EVZIO?

EVZIO may cause serious side effects, including:

Common side effects of EVZIO include dizziness and injection site redness.

These are not all of the possible side effects of EVZIO. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click for full Prescribing Information and Patient Information.

What is EVZIO?

EVZIO is a prescription medicine used in adults and children for the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond. EVZIO is to be given right away and does not take the place of emergency medical care. Get emergency medical help right away after the first dose of EVZIO, even if the person wakes up. EVZIO is safe and effective in children for known or suspected opioid overdose.

Important Safety Information

What is the most important information I should know about EVZIO?

EVZIO is used to temporarily reverse the effects of opioid medicines. The medicine in EVZIO has no effect in people who are not taking opioid medicines. Always carry EVZIO with you in case of an opioid emergency.

INDICATION

What is EVZIO?

EVZIO is a prescription medicine used in adults and children for the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.

EVZIO is to be given right away and does not take the place of emergency medical care. Get emergency medical help right away after the first dose of EVZIO, even if the person wakes up.

EVZIO is safe and effective in children for known or suspected opioid overdose.