Anywhere opioids are present there may be a risk of opioid overdose1-4
Deaths due to opioid overdose have continued to increase.5-7
Deaths due to opioid overdose are a continuing public health crisis that affects people of all races, genders, socioeconomic levels, and geographic regions.
~130 people a day—approximately one person every 11 minutes—died due to opioid overdoses in 2017.3
Know the risks
Be aware that factors in a person's everyday life can increase the risk for experiencing or witnessing an opioid overdose.8,9
People, places, and things (eg, a restaurant, a film, an image, celebratory events)8,9
Stressful life-events (eg, death of a loved one, divorce, loss of a job)8,9
During or after treatment when you return to the circle of friends and surroundings where you used opioids before8,9
Also know that certain people have higher risk for opioid overdose, including those who10,11:
- Misuse prescription opioids (like oxycodone) or use heroin or other illicit opioids (like fentanyl or carfentanil)
- Were just discharged from detoxification or a treatment facility without medication treatment or stop taking medication treatment
- Recently received emergency medical care for an opioid overdose
- Were recently released from prison and have a history of opioid misuse or addiction
- Use opioids along with alcohol or certain medications (like benzodiazepines)
EVZIO—an auto-injector designed to be easy to use—provides simple, on-the-spot voice and visual guidance to help those with no medical training administer naloxone during an opioid overdose.
EVZIO is not a substitute for emergency medical care.
Talk to your healthcare professional to learn more about EVZIO.
You also can call 1-855-77-EVZIO (1-855-773-8946) for more information about EVZIO.
- EVZIO [prescribing information]. Richmond, VA: kaleo, Inc.; 2016.
- Substance Abuse and Mental Health Services Administration. SAMHSA Opioid Overdose Prevention Toolkit. HHS Publication No. (SMA) 16-4742. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2018.
- Centers for Disease Control and Prevention. CDC Wonder: About multiple causes of death, 1999-2017. http://wonder.cdc.gov/mcd-icd10.html. Accessed January 28, 2019.
- Federation of State Medical Boards. Guidelines for the chronic use of opioids. https://www.fsmb.org/siteassets/advocacy/policies/opioid_guidelines_as_adopted_april-2017_final.pdf. Accessed January 28, 2019.
- Centers for Disease Control and Prevention. Today’s heroin epidemic: overdose prevention. https://www.cdc.gov/drugoverdose/opioids/heroin.html. Accessed January 28, 2019.
- Centers for Disease Control and Prevention. Drug overdose. https://www.cdc.gov/drugoverdose/data/index.html. Accessed January 28, 2019.
- U.S. Department of Health and Human Services. What is the U.S. opioid epidemic? https://www.hhs.gov/opioids/about-the-epidemic/index.html. January 28, 2019.
- National Institute on Drug Abuse. Drugs, brains, and behavior: The science of addiction. NIH Pub No.14-5605. Printed April 2007, Revised July 2014. https://d14rmgtrwzf5a.cloudfront.net/sites/default/files/soa_2014.pdf. Accessed January 28, 2019.
- Data on file. Richmond, VA: kaleo Inc.
- US Department of Health & Human Services. Surgeon General’s advisory on naloxone and opioid overdose. https://www.surgeongeneral.gov/priorities/opioid-overdose-prevention/naloxone-advisory.html. Accessed January 28, 2019.
- World Health Organization. Management of substance abuse. Information sheet on opioid overdose. November 2014. http://www.who.int/substance_abuse/information-sheet/en/. Accessed January 28, 2019.